Description
Responsibilities:Hands-on generation of data using laboratory techniques such as X-ray diffraction, thermal analysis, vibrational spectroscopy, Laser diffraction particle size analysis, electron microscopy, liquid chromatography, shear cell testing, compaction simulation, etc.
Hands-on generation of data using small scale manufacturing technologies such as blending, granulation, milling, tablet compaction, encapsulation, film coating, etc.
Preparation of prototype formulations (solutions, suspensions, tablets, capsules, etc.) for exploratory studies in in-vitro and in-vivo models.
Evaluation of the robustness of prototype drug product manufacturing processes.
Analysis of solid and liquid samples for key physical and chemical properties (such as solubility, static charge, sticking potential, segregation tendency, etc.).
Accurate record keeping of the above activities using electronic databases, notebooks and document management systems.
Calculation of derived parameters and properties from primary data.
Scale-up and scale-down of drug product manufacturing processes using engineering models and computer simulations.
Maintaining and calibrating complex instrumentation
Working in a GLP or GMP environment with appropriate documentation and safety practices.
Evaluation of new equipment/technology.
Implementation of new experimental methods and/or use of new equipment.
SKILLS:
Qualifications
BS, MS or PhD in chemistry, engineering, biology, pharmacy, materials science, physics, computer science or related field.