Director, Bioinformatics Core

Oregon  ‐ Onsite
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Description

Job Title: Director, Bioinformatics Core

Department/program: Computational Biology Department, OHSU School of Medicine

The Computational Biology Program at Oregon Health and Science University (OHSU), Portland, OR is committed to leading the development of next-generation patient care through discoveries made by big data analytics, enabled by open collaboration,highly integrated team science, and professional bioinformatics services for our researchers.
As a critical aspect of achieving this mission, we are seeking a bioinformatics leader to direct and help expand our OHSU bioinformatics core. The bioinformatics core is dedicated to providing outstanding professional services to our researchers in need of informatics solutions and consulintg support for data management and analysis pipelines of commonly used omics and imaging data types.The bioinformatics core director is expected to lead a professional services team, following best practices for consulting that includes understanding and fitting solutions to needs, estimating efforts and skills, contributing high value to proposals and creating high quality deliverables for study project reports and publications. The bioinformatics core leader is expected to integrate team members and employ software engineering practices to develop strong standards for quality and reuse. Deliverables created in support of OHSU researchers should serve as standards for quality and innovation in broader communities building informatics tools for big data management, omics and imaging analyses, and clinical data integration. In particular, core output under the director should contribute to the design and development of international standardized APIs and data schemas as well as compatible implementations that function well in the emerging community ecosystem of bioinformatics software tools.

The Knight Cancer Institute at OHSU is an international leader in cancer research and precision treatment. The institute's director, Brian Druker, M.D., helped usher in the era of precision cancer medicine with his discovery that cancer cells could be shut down by disabling the molecules that drive their growth without harming healthy cells. The institute continues to build upon its scientific and clinical leadership; both public support and private philanthropy have provided crucial resources to advance its progress. Most recently, Dr. Druker's plans to advance the early detection of cancer inspired Nike Co-Founder Phil Knight and his wife Penny to pledge a $500 million donation if OHSU raises an additional $500 million as part of a two-year fundraising campaign. The OHSU Knight Cancer Institute is also attracting powerful research collaborations with technology leaders such as Intel Corporation and FEI Co., who want to be part of the Knight's mission to end cancer as we know it.

OHSU provides substantial resources to enable data intensive science, including a world-class exascale super computing cluster, close interactions and resource commitments by leading technology companies such as Intel, tight integration with clinical and basic research programs across campus, graduate training programs in quantitative biosciences, biostatistics, biomedical informatics, bioinformatics and computational biology, and substantial long-term resource commitments, including the $1 billion Phil and Penny Knight "challenge" to support cancer research, with a significant focus on computation.

Responsibilities
•Oversee the bioinformatics core team, which will:
oDevelop custom analytics and data management applications to facilitate: large-scale omics data analysis; machine learning methods to infer genotype-to-phenotype predictive models; analysis of quantitative imaging data.
oProvide informatics services to investigators across campus, including pre-experiment consulting, application and training on the use of bioinformatics core software tools, and integration of user-generated and large-scale public data sets.
oMaintain well-curated, highly structured, transparent omics, imaging, or clinical data resources.
oImplement scalable cloud-enabled workflows to disseminate analytical advances to the research community.
oEstablish and maintain standards for structured software & systems engineering, including requirements, design, code, test, quality, configuration & release management and project management.
oAssess, test, and implement best practices for omics and imaging data analysis.
oProvide documentation and user support allowing computational researchers across campus to access and re-use analysis tools.
oDevelop tools to integrate commonly used open source bioinformatics software applications.
oParticipate in leading international efforts aimed at establishing best practices and standards for genomic, imaging, and clinical data representation and analysis.
•Work with research leaders and key stakeholders across campus to prioritize bioinformatics core services to best meet user needs.
•Develop funding model for expansion and sustainability of the core, including investments from organizational units across campus; charge-back models; and collaborative grant applications.
•Develop staffing plans and oversee recruitments as needed.
•Establish scientific collaborations with researchers across campus.
•Work closely with multiple stakeholders and collaborators across campus, including experimental and computational faculty and researchers, as well as systems administrators and other software development groups.
•Lead and collaborate on grant applications related to bioinformatics core projects.

Start date
As soon as possible
From
Oregon Health and Science University
Published at
22.01.2015
Project ID:
838797
Contract type
Freelance
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